@Alan_Watson_ @OurSacredGrove @Veganella_ If you calculate the human equivalent dose according to this https://t.co/42uZq4Zqaz you end up with 6 g. This dose is achievable by supplementation and considered safe by the European Food Safety Authority.
@RealHaraldJezek @BradSchoenfeld Thanks for the comments. This paper describes how to convert mouse into human doses. If you do so you end up with roughly 6 g taurine/day in a human. https://t.co/42uZq4Zqaz This dose of 6 g taurine/day is also the observe
In relation to https://t.co/kiiSVMec3b two important questions are: Can humans safely achieve equivalent doses? If you use the appropriate conversion formula (https://t.co/Lfwg7ZBiZW) then the T1000 and T500 doses are roughly 6 and 3 g in humans.
@DorylisK @MaxDelvallee Gardez à l’esprit que la transposition souris-humain n’est pas une règle de 3 mais est grossi-modo divisée par 10, soit 0,5mg/kg ce qui serait compatible avec une utilisation clinique, sans pré-juger de l’efficacité dans la patholog